Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979557 | 0.98 | CES2 (0.45) | POLBALDH1A1GAAKDM4ECNR2 | |
| SCHEMBL5281391 | 0.95 | POLB (0.48) | POLBALDH1A1GAAKDM4ECNR2 | |
| SCHEMBL6567717 | 0.91 | ALDH1A1 (0.52) | POLBALDH1A1GAAKDM4ECNR2 | |
| SCHEMBL6569140 | 0.89 | ALDH1A1 (0.50) | POLBALDH1A1GAAKDM4ECNR2 | |
| SCHEMBL6566239 | 0.89 | ALDH1A1 (0.50) | POLBALDH1A1GAAKDM4ECNR2 | |
| SCHEMBL6567797 | 0.89 | ALDH1A1 (0.50) | POLBALDH1A1GAAKDM4ECNR2 | |
| SCHEMBL6568005 | 0.89 | ALDH1A1 (0.50) | POLBALDH1A1GAAKDM4ECNR2 | |
| SCHEMBL6568014 | 0.89 | ALDH1A1 (0.50) | POLBALDH1A1GAAKDM4ECNR2 | |
| SCHEMBL6567299 | 0.89 | ALDH1A1 (0.50) | POLBALDH1A1GAAKDM4ECNR2 | |
| SCHEMBL6567779 | 0.89 | ALDH1A1 (0.50) | POLBALDH1A1GAAKDM4ECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538039-A | Synthetic method of 3-fluoroindolone compound | 福州大学 | 2021-03-23 | — | — | CN | disclosed |