Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.45 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688951 | 0.90 | TEAD1 (0.50) | TAAR1TEAD1TEAD3KCNA3NFE2L2 | |
| SCHEMBL5537516 | 0.83 | TDP1 (0.46) | — | |
| SCHEMBL4980425 | 0.80 | TEAD1 (0.56) | TAAR1TEAD1TEAD3KCNA3NFE2L2 | |
| SCHEMBL13103169 | 0.75 | NFE2L2 (0.69) | TAAR1TEAD1TEAD3KCNA3NFE2L2 | |
| SCHEMBL2301274 | 0.75 | CARM1 (0.49) | — | |
| SCHEMBL5519659 | 0.75 | TEAD1 (0.52) | TAAR1TEAD1TEAD3KCNA3NFE2L2 | |
| SCHEMBL1365368 | 0.74 | CTSS (0.44) | — | |
| SCHEMBL3154460 | 0.73 | TDP1 (0.43) | — | |
| SCHEMBL8529857 | 0.72 | LTA4H (0.50) | TAAR1TEAD1TEAD3KCNA3NFE2L2 | |
| SCHEMBL5722054 | 0.72 | TEAD1 (0.54) | TAAR1TEAD1TEAD3KCNA3NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |