Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.45 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979690 | 0.84 | ATM (0.53) | ATML3MBTL1RAB9AHRH2HRH1 | |
| SCHEMBL10817906 | 0.75 | RAB9A (0.76) | ATML3MBTL1RAB9AHRH2HRH1 | |
| SCHEMBL18824538 | 0.75 | ATM (0.81) | ATML3MBTL1HRH1KDM4ERECQL | |
| SCHEMBL18824776 | 0.75 | ATM (0.87) | ATML3MBTL1HRH1KDM4ERECQL | |
| SCHEMBL7244819 | 0.74 | HRH2 (0.71) | RAB9AHRH2HRH1HRH3 | |
| SCHEMBL7250885 | 0.74 | HRH2 (0.71) | RAB9AHRH2HRH1HRH3 | |
| SCHEMBL7976330 | 0.74 | HRH2 (0.71) | RAB9AHRH2HRH1HRH3 | |
| SCHEMBL10813890 | 0.73 | ALDH1A1 (0.63) | ATML3MBTL1RAB9AHRH1TDP1 | |
| SCHEMBL491581 | 0.73 | ATM (0.90) | ATML3MBTL1HRH1LTA4HPTGS2 | |
| SCHEMBL1776837 | 0.73 | ATM (0.90) | ATML3MBTL1HRH1LTA4HPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066534-A2 | CYCLIC AND BICYCLIC DIAMINO HISTAMINE-3 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | claimed |