Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 2/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979965 | 0.81 | NAMPT (0.45) | ALDH1A1P2RX7NAMPTMEN1KMT2A | |
| SCHEMBL14324450 | 0.73 | NAMPT (0.59) | ALDH1A1NAMPTMEN1KMT2A | |
| SCHEMBL2458903 | 0.73 | NAMPT (0.59) | ALDH1A1NAMPTMEN1KMT2A | |
| SCHEMBL161796 | 0.71 | NAMPT (0.64) | NAMPT | |
| SCHEMBL6400150 | 0.71 | P2RX7 (0.71) | ALDH1A1P2RX7MEN1KMT2APABPC1 | |
| SCHEMBL6400149 | 0.71 | P2RX7 (0.71) | ALDH1A1P2RX7MEN1KMT2APABPC1 | |
| SCHEMBL7976375 | 0.69 | NAMPT (0.58) | ALDH1A1NAMPTTUBBHTT | |
| SCHEMBL8195019 | 0.69 | NAMPT (0.58) | ALDH1A1NAMPTTUBBHTT | |
| SCHEMBL5125750 | 0.69 | MEN1 (0.60) | ALDH1A1MEN1KMT2APABPC1EIF4H | |
| SCHEMBL17322585 | 0.68 | HTT (0.41) | ALDH1A1NAMPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |