Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7241379 | 1.00 | ERN1 (0.56) | ERN1ACHEENPP2MAPTGAA | |
| SCHEMBL7980067 | 0.83 | ERN1 (0.45) | ERN1ACHEENPP2MAPTGAA | |
| SCHEMBL7980070 | 0.82 | ERN1 (0.47) | ERN1ACHEENPP2MAPTGAA | |
| SCHEMBL562147 | 0.82 | ERN1 (0.63) | ERN1ACHEMAPTGAAKMT2A | |
| SCHEMBL1126254 | 0.81 | ACHE (0.48) | ERN1ACHEENPP2MAPTGAA | |
| SCHEMBL29951600 | 0.79 | ACHE (0.64) | ERN1ACHEENPP2MAPTKMT2A | |
| SCHEMBL10053939 | 0.78 | SELL (0.62) | ERN1ACHEMAPTGAAKMT2A | |
| SCHEMBL15726336 | 0.78 | ACHE (0.45) | ERN1ACHEENPP2MAPTGAA | |
| SCHEMBL8709932 | 0.76 | ACHE (0.52) | ERN1ACHEENPP2MAPTGAA | |
| SCHEMBL7520392 | 0.76 | ERN1 (0.57) | ERN1ACHEMAPTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177419-B1 | ANTIOXIDANT CHELATE COMPOUNDS FOR PREVENTING OXYGEN FREE RADICAL-ASSOCIATED DISEASES IN MAMMALS; NEUROPROTECTANTS, SUPEROXIDE DISMUTASE (SOD), CATALASE (CAT) AND/OR PEROXIDASE (POD) MIMETICS | EUKARION, INC. | 2001-01-23 | — | — | US | disclosed |