Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.34 |
| ▸ | TUBB | P07437 | 2/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980063 | 0.83 | ERN1 (0.56) | ERN1ACHEMAPTKMT2AKDM4E | |
| SCHEMBL7241379 | 0.83 | ERN1 (0.56) | ERN1ACHEMAPTKMT2AKDM4E | |
| SCHEMBL29951600 | 0.79 | ACHE (0.64) | ERN1ACHEMAPTCYP3A4KMT2A | |
| SCHEMBL7980070 | 0.78 | ERN1 (0.47) | ERN1ACHEMAPTKMT2AKDM4E | |
| SCHEMBL7776334 | 0.76 | KDM4E (0.37) | MAPTKMT2AKDM4EALDH1A1POLB | |
| SCHEMBL562147 | 0.71 | ERN1 (0.63) | ERN1ACHEMAPTCYP3A4KMT2A | |
| SCHEMBL31090995 | 0.70 | ACHE (0.60) | ERN1ACHEMAPTCYP3A4KMT2A | |
| SCHEMBL1126254 | 0.70 | ACHE (0.48) | ERN1ACHEMAPTCYP3A4KMT2A | |
| SCHEMBL7772570 | 0.70 | ENPP2 (0.50) | ERN1MAPTCYP3A4KMT2AKDM4E | |
| Boric Acid SCHEMBL4626813 | 0.69 | ACHE (0.81) | ERN1ACHEMAPTCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177419-B1 | ANTIOXIDANT CHELATE COMPOUNDS FOR PREVENTING OXYGEN FREE RADICAL-ASSOCIATED DISEASES IN MAMMALS; NEUROPROTECTANTS, SUPEROXIDE DISMUTASE (SOD), CATALASE (CAT) AND/OR PEROXIDASE (POD) MIMETICS | EUKARION, INC. | 2001-01-23 | — | — | US | disclosed |