SCHEMBL79801

SCHEMBL79801

NC(=O)[N]c1cccc2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 8/20 0.49
GRIN2D O15399 1/20 0.49
GRIN3B O60391 1/20 0.49
GRIN1 Q05586 1/20 0.49
GRIN2A Q12879 1/20 0.49
GRIN2B Q13224 1/20 0.49
GRIN2C Q14957 1/20 0.49
GRIN3A Q8TCU5 1/20 0.49
KDM4E B2RXH2 1/20 0.48
GAA P10253 1/20 0.48
SCN2A Q99250 1/20 0.47
F2 P00734 2/20 0.46
PLG P00747 1/20 0.46
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
ABCB11 O95342 1/20 0.46
ALDH1A1 P00352 1/20 0.46
NR3C1 P04150 1/20 0.46
ADRA2A P08913 1/20 0.46
ADORA3 P0DMS8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3112899 0.89 HPRT1 (0.48) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL3126787 0.83 KDM4E (0.56) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL343533 0.82 NR4A1 (0.50) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8058998 0.80 ALDH1A1 (0.50) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL834358 0.80 ALDH1A1 (0.46) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL283065 0.76 ALDH1A1 (0.44) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL4172132 0.76 SIGMAR1 (0.43) SIGMAR1SCN2ACYP1A2CYP3A4ABCB11
SCHEMBL7449481 0.76 DHODH (0.45) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL2804173 0.75 SIGMAR1 (0.61) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7445149 0.74 SIGMAR1 (0.42) SIGMAR1KDM4ESCN2ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 771 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9935269-B2 Electroluminescence element Konica Minolta, Inc. (JP) 2018-04-03 US claimed
US-5401766-A Hypotensive agents with vasodilation HOECHST AKTIENGESELLSCHAFT (DE) 1995-03-28 US claimed
US-5158959-A Treatment of hypertension HOECHST AKTIENGESELLSCHAFT (DE) 1992-10-27 US claimed
EP-0201027-B1 SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1992-06-24 EP claimed
US-4692400-A CONTAINING A UREIDO- AND ACYLAMINO-CONTAINING PHENOL-TYPE CYAN COUPLER AND NEGATIVE-TYPE CORESHELL SILVER HALIDE GRAINS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1987-09-08 US claimed
EP-0102821-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1987-04-08 EP claimed
EP-0204416-A2 Light-sensitive silver halide color photographic material KONICA CORPORATION (JP) 1986-12-10 EP claimed
EP-0201027-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1986-11-12 EP claimed
US-4594314-A Containing phenol-type cyan coupler KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-06-10 US claimed
EP-0102821-A1 Silver halide color photographic light-sensitive material KONICA CORPORATION (JP) 1984-03-14 EP claimed
US-4292238-A Alkylation of benzthiazole-azo-phenylamine dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1981-09-29 US claimed
US-4021428-A 4-Piperidino-5-oxo-2-pyrazolines FUJI PHOTO FILM CO., LTD. (JA) 1977-05-03 US claimed
US-3956339-A 4-Pyridinio-5-pyrazolone salts, process for their preparation and their use FUJI PHOTO FILM CO., LTD. (JA) 1976-05-11 US claimed
JP-1269937-A None JP disclosed
JP-2090151-A None JP disclosed
JP-62054256-A None JP disclosed
EP-0102821-A1 Silver halide color photographic light-sensitive material KONICA CORPORATION (JP) 1984-03-14 EP disclosed
JP-S5833252-A SILVER HALIDE COLOR PHOTOGRAPHIC CYAN COUPLER KONISHIROKU PHOTO IND CO LTD 1983-02-26 JP disclosed
US-4021428-A 4-Piperidino-5-oxo-2-pyrazolines FUJI PHOTO FILM CO., LTD. (JA) 1977-05-03 US disclosed
US-3956339-A 4-Pyridinio-5-pyrazolone salts, process for their preparation and their use FUJI PHOTO FILM CO., LTD. (JA) 1976-05-11 US disclosed