Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | BID | P55957 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978811 | 0.91 | PTPN1 (0.46) | PTPN1TACR1TP53LMNAMEN1 | |
| SCHEMBL7985518 | 0.85 | LMNA (0.51) | PTPN1TP53LMNAMEN1TSHR | |
| SCHEMBL9231093 | 0.80 | BID (0.42) | TACR1TP53BIDMCL1BCL2L1 | |
| SCHEMBL1954009 | 0.80 | NPY2R (0.42) | PTPN1NPY2RBIDMCL1BCL2L1 | |
| SCHEMBL31518126 | 0.80 | AKR1B1 (0.47) | PTPN1LMNAMEN1TSHRKMT2A | |
| SCHEMBL5809365 | 0.79 | CYP3A4 (0.42) | TP53NPY2RBIDMCL1BCL2L1 | |
| SCHEMBL27463138 | 0.78 | PTPN1 (0.59) | PTPN1LMNANPY2RMEN1TSHR | |
| SCHEMBL10759132 | 0.77 | TSHR (0.48) | MEN1TSHRKMT2APPARA | |
| SCHEMBL3218535 | 0.76 | NPY2R (0.44) | NPY2RBIDMCL1BCL2L1BAK1 | |
| SCHEMBL28211185 | 0.76 | CYP3A4 (0.41) | TP53NPY2RCYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |