SCHEMBL3218535

SCHEMBL3218535

CCCCc1ccccc1N(C)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPY2R P49146 1/20 0.44
BID P55957 3/20 0.42
MCL1 Q07820 3/20 0.42
BCL2L1 Q07817 2/20 0.42
BAK1 Q16611 2/20 0.42
KAT8 Q9H7Z6 2/20 0.42
PPARA Q07869 2/20 0.42
PPARG P37231 1/20 0.42
EP300 Q09472 1/20 0.42
KAT2A Q92830 1/20 0.42
KAT2B Q92831 1/20 0.42
KAT5 Q92993 1/20 0.42
SAE1 Q9UBE0 1/20 0.42
LIPG Q9Y5X9 1/20 0.41
CYSLTR2 Q9NS75 5/20 0.40
CYSLTR1 Q9Y271 5/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9142099 0.85 PTPN1 (0.37) NPY2R
SCHEMBL8751654 0.84 LMNA (0.43)
SCHEMBL11509339 0.83 PTPN1 (0.35) NPY2RCYSLTR2CYSLTR1
SCHEMBL11210492 0.81 PTPN1 (0.38)
SCHEMBL11466300 0.81 NPY2R (0.48) NPY2RBIDMCL1BCL2L1BAK1
SCHEMBL30957409 0.80 NPY2R (0.53) NPY2RBIDMCL1BCL2L1BAK1
SCHEMBL7705866 0.79 ALDH1A1 (0.39)
SCHEMBL5865850 0.78 POLB (0.38)
SCHEMBL14840424 0.78 LIPG (0.44) NPY2RLIPG
SCHEMBL2903423 0.78 LIPG (0.48) NPY2RBIDMCL1BCL2L1BAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5866514-A HIGH BOILING; ODORLESS; ANTISEPTICS, HERBICIES, INSECTICIDES NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1999-02-02 US claimed
JP-62185004-A None JP disclosed
JP-8225415-A None JP disclosed
JP-55081803-A None JP disclosed
JP-55081802-A None JP disclosed
EP-2132987-B1 NEMATICIDAL AGENT COMPOSITION AND METHOD OF USING THE SAME NIHON NOHYAKU CO LTD (JP) 2016-04-06 EP disclosed
US-8648101-B2 Nematicidal agent composition and method of using the same NIHON NOHYAKU CO., LTD. (JP) 2014-02-11 US disclosed
US-20100048647-A1 NEMATICIDAL AGENT COMPOSITION AND METHOD OF USING THE SAME NIHON NOHYAKU CO., LTD. (JP) 2010-02-25 US disclosed
EP-2132987-A1 NEMATICIDAL AGENT COMPOSITION AND METHOD OF USING THE SAME Nihon Nohyaku CO., LTD. (JP) 2009-12-16 EP disclosed
EP-1180106-A1 4-SUBSTITUTED MILBEMYCIN DERIVATIVES Novartis AG (CH) 2002-02-20 EP disclosed
EP-0753255-A2 Pesticidal compositions comprising diarylalkanes NIPPON PETROCHEMICALS CO., LTD. (JP) 1997-01-15 EP disclosed
JP-H08225415-A ANTIMICROBIAL LIQUID AGENT FOR CEMENT AND GYPSUM NIPPON MIZUSHIYORI GIKEN:KK 1996-09-03 JP disclosed
EP-0431968-A1 Oxetane derivatives, their preparation and their use as anti-fungal or fungicidal agents Sankyo Company Limited (JP) 1991-06-12 EP disclosed
EP-0196524-B1 PHENOXYALKYLAMINOPYRIMIDINE DERIVATIVES, THEIR PREPARATION AND INSECTICIDAL AND ACARICIDAL COMPOSITIONS CONTAINING THEM SANKYO COMPANY LIMITED (JP) 1990-03-07 EP disclosed
JP-S62185004-A INSECTICIDAL COMPOSITION FOR LISSORHOPTRUS ORYZOPHILUS YASHIMA CHEM IND CO LTD 1987-08-13 JP disclosed
EP-0103114-B1 THIENOPYRIDINE DERIVATIVES, THEIR PREPARATION AND INSECTICIDAL AND ACARICIDAL COMPOSITIONS CONTAINING THEM SANKYO COMPANY LIMITED (JP) 1986-11-12 EP disclosed
JP-S5581803-A REPELLENT WITH DURABILITY IDEMITSU KOSAN CO LTD 1980-06-20 JP disclosed
JP-S5581802-A REPELLENT WITH DURABILITY IDEMITSU KOSAN CO LTD 1980-06-20 JP disclosed
US-4035488-A Insecticidal and acaricidal substituted phenyl thiophosphoric acid esters CIBA-GEIGY CORPORATION (US) 1977-07-12 US disclosed
US-3948940-A Pesticidal phthalimido phosphorous ester compounds CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048647-A1 NEMATICIDAL AGENT COMPOSITION AND METHOD OF USING THE SAME HDHD5, NAAA, ATL3 NPY2R 532/4885BID 2100/4885MCL1 1979/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.