Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CCR1 | P32246 | 3/20 | 0.48 |
| ▸ | CCR5 | P51681 | 3/20 | 0.48 |
| ▸ | CCR8 | P51685 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910798 | 0.81 | KDM4E (0.46) | KDM4ENPC1RAB9AL3MBTL1ALOX15 | |
| SCHEMBL30802290 | 0.78 | KDM4E (0.54) | KDM4ENPC1RAB9AGLAMAPT | |
| SCHEMBL844746 | 0.78 | KDM4E (0.54) | KDM4ENPC1RAB9AGLAMAPT | |
| SCHEMBL4876602 | 0.78 | KDM4E (0.43) | KDM4ENPC1RAB9AGLAMAPT | |
| SCHEMBL15436237 | 0.76 | PIM1 (0.45) | KDM4ENPC1RAB9AGLAHTT | |
| SCHEMBL6212390 | 0.76 | KDM4E (0.52) | KDM4EL3MBTL1ALOX15LMNACCR1 | |
| Hydrochloric Acid SCHEMBL15436253 | 0.74 | PIM1 (0.44) | KDM4ENPC1RAB9AGLAHTT | |
| SCHEMBL11965541 | 0.74 | KDM4E (0.68) | KDM4ENPC1RAB9AGLAMAPT | |
| SCHEMBL489080 | 0.74 | KDM4E (0.71) | KDM4ENPC1RAB9AGLAMAPT | |
| SCHEMBL30215997 | 0.74 | KDM4E (0.71) | KDM4ENPC1RAB9AGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035055-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-22 | — | — | WO | disclosed |
| CN-1190453-C | Polymer of aromatic amine-2,3-pyridine diketone, its preparing method and usage | UNIV ZHONGSHAN (CN) | 2005-02-23 | — | — | CN | disclosed |
| CN-1431242-A | Polymer of aromatic amine-2,3-pyridine diketone, its preparing method and usage | UNIV ZHONGSHAN (CN) | 2003-07-23 | — | — | CN | disclosed |