Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.30 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.30 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | CBX7 | O95931 | 1/20 | 0.30 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.30 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.30 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964514 | 0.80 | TSHR (0.31) | TSHRHTTTP53MDM2 | |
| SCHEMBL17076839 | 0.80 | HTT (0.42) | TSHRCYP19A1HTTKMOREN | |
| SCHEMBL17076828 | 0.74 | TSHR (0.33) | TSHRHTTKMORENPLK1 | |
| SCHEMBL8878968 | 0.74 | HTT (0.44) | TSHRCYP19A1HTTKMOPLK1 | |
| SCHEMBL13924120 | 0.74 | PDE3B (0.39) | REN | |
| SCHEMBL7964481 | 0.73 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL7964502 | 0.71 | — | — | |
| SCHEMBL9378956 | 0.70 | TSHR (0.59) | TSHRHTTALDH1A1CBX7CDYL2 | |
| SCHEMBL7978010 | 0.69 | DRD2 (0.32) | — | |
| SCHEMBL10423074 | 0.69 | GRM5 (0.39) | TSHRGRM5CBX7CDYL2CDYL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030782-A2 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-05-03 | — | — | WO | disclosed |