SCHEMBL7964514

SCHEMBL7964514

C#CCN1C(=O)COc2ccc(N=C=O)nc21

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.31
HTT P42858 1/20 0.30
TP53 P04637 1/20 0.30
MDM2 Q00987 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7980643 0.80 TSHR (0.36) TSHRHTTTP53MDM2
SCHEMBL9478294 0.74 HTT (0.41) TSHRHTT
SCHEMBL7964481 0.69 ALDH1A1 (0.31)
SCHEMBL1276934 0.68 CHRM1 (0.37) TSHRHTT
SCHEMBL9378956 0.66 TSHR (0.59) TSHRHTT
SCHEMBL7978010 0.66 DRD2 (0.32)
SCHEMBL10423074 0.66 GRM5 (0.39) TSHR
SCHEMBL7964502 0.65
SCHEMBL7980627 0.65
SCHEMBL9383001 0.65 KMO (0.61) TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001030782-A2 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-05-03 WO disclosed