Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971233 | 0.82 | MAPT (0.48) | HSD11B1TAS1R3TAS1R1F10NPC1 | |
| Hydrochloric Acid SCHEMBL7987810 | 0.81 | MAPT (0.47) | HSD11B1TAS1R3TAS1R1F10NPC1 | |
| Hydrochloric Acid SCHEMBL7970754 | 0.78 | HSD11B1 (0.45) | HSD11B1F10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7984156 | 0.76 | HSD11B1 (0.61) | HSD11B1SMN1; SMN2RXFP1PRNPCYP2C19 | |
| SCHEMBL7970877 | 0.72 | HSD11B1 (0.51) | HSD11B1F10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13963145 | 0.72 | HSD11B1 (0.62) | HSD11B1F10SMN1; SMN2RXFP1PRNP | |
| SCHEMBL13589546 | 0.72 | CYP2C19 (0.56) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL4834908 | 0.72 | HSD11B1 (0.62) | HSD11B1F10SMN1; SMN2RXFP1PRNP | |
| Hydrochloric Acid SCHEMBL7970822 | 0.71 | HSD11B1 (0.46) | HSD11B1NPC1RAB9ASMN1; SMN2RXFP1 | |
| SCHEMBL4775261 | 0.70 | HSD11B1 (0.61) | HSD11B1F10SMN1; SMN2RXFP1PRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |