Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | OGG1 | O15527 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7987810 | 0.99 | MAPT (0.47) | MAPTNPC1RAB9ASMN1; SMN2HSD11B1 | |
| Hydrochloric Acid SCHEMBL7970754 | 0.86 | HSD11B1 (0.45) | NPC1RAB9ASMN1; SMN2HSD11B1RXFP1 | |
| SCHEMBL7980700 | 0.82 | HSD11B1 (0.47) | MAPTNPC1RAB9ASMN1; SMN2HSD11B1 | |
| SCHEMBL7984156 | 0.77 | HSD11B1 (0.61) | MAPTSMN1; SMN2HSD11B1RXFP1PRNP | |
| SCHEMBL7970877 | 0.76 | HSD11B1 (0.51) | MAPTNPC1RAB9ASMN1; SMN2HSD11B1 | |
| SCHEMBL7971230 | 0.73 | HSD11B1 (0.48) | MAPTNPC1RAB9ASMN1; SMN2HSD11B1 | |
| SCHEMBL4834908 | 0.72 | HSD11B1 (0.62) | MAPTSMN1; SMN2HSD11B1RXFP1PRNP | |
| SCHEMBL13963145 | 0.72 | HSD11B1 (0.62) | MAPTSMN1; SMN2HSD11B1RXFP1PRNP | |
| Hydrochloric Acid SCHEMBL7987803 | 0.72 | HSD11B1 (0.47) | MAPTNPC1RAB9ASMN1; SMN2HSD11B1 | |
| SCHEMBL1509582 | 0.72 | TBXAS1 (0.53) | SMN1; SMN2HSD11B1RXFP1PRNPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | claimed |