Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984156 | 0.77 | HSD11B1 (0.61) | HSD11B1RXFP1PRNPALDH1A1LMNA | |
| SCHEMBL7971233 | 0.76 | MAPT (0.48) | HSD11B1RXFP1PRNPALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7987810 | 0.75 | MAPT (0.47) | HSD11B1RXFP1PRNPALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7970754 | 0.74 | HSD11B1 (0.45) | HSD11B1RXFP1PRNPALDH1A1LMNA | |
| SCHEMBL7981221 | 0.73 | HSD11B1 (0.53) | HSD11B1RXFP1PRNPALDH1A1LMNA | |
| SCHEMBL4834908 | 0.72 | HSD11B1 (0.62) | HSD11B1RXFP1PRNPALDH1A1LMNA | |
| SCHEMBL13963145 | 0.72 | HSD11B1 (0.62) | HSD11B1RXFP1PRNPALDH1A1LMNA | |
| SCHEMBL7980700 | 0.72 | HSD11B1 (0.47) | HSD11B1RXFP1PRNPALDH1A1LMNA | |
| SCHEMBL7984329 | 0.72 | HSD11B1 (0.62) | HSD11B1RXFP1PRNPALDH1A1LMNA | |
| SCHEMBL2526384 | 0.72 | RXFP1 (0.49) | HSD11B1RXFP1PRNPALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |