Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | BCL9 | O00512 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980755 | 0.69 | MAPT (0.36) | KDM4EPKMHPGDHSD17B10ALDH1A1 | |
| SCHEMBL27660661 | 0.66 | ALOX15 (0.39) | KDM4EHSD17B10ALDH1A1ALOX15BCL9 | |
| SCHEMBL7982607 | 0.65 | ADORA2A (0.43) | KDM4EHPGDHSD17B10ALDH1A1RAB9A | |
| SCHEMBL6624655 | 0.64 | L3MBTL1 (0.41) | PKMALDH1A1ALOX15BCL9CTNNB1 | |
| SCHEMBL27750732 | 0.63 | ALDH1A1 (0.38) | KDM4EHSD17B10ALDH1A1ALOX15BCL9 | |
| SCHEMBL28369356 | 0.62 | ALDH1A1 (0.36) | KDM4EHSD17B10ALDH1A1ALOX15BCL9 | |
| SCHEMBL9737854 | 0.61 | ALDH1A1 (0.43) | KDM4EHSD17B10ALDH1A1ALOX15BCL9 | |
| SCHEMBL27518195 | 0.61 | SMN1; SMN2 (0.48) | HPGDHSD17B10ALDH1A1ALOX15BCL9 | |
| SCHEMBL7983188 | 0.60 | ALDH1A1 (0.48) | KDM4EPKMHPGDHSD17B10ALDH1A1 | |
| SCHEMBL2254046 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174877-B1 | EXCELLANT BACTERICIDES, ORAL ABSORBABILITY AND STABILITY; IMPROVE THE STABILITY TO RENAL DEHYDROPEPTIDASE I (DHP-I); 2-(2-(N-HETEROCYCLIC-ETHYLTHIO-) DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0876370-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997025325-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-17 | — | — | WO | disclosed |