Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798317 | 0.92 | ALPL (0.44) | ALPLLMNASLC40A1KMT2APIK3CA | |
| SCHEMBL15648486 | 0.90 | ALPL (0.42) | ALPLLMNAKDM4EHSD17B10KMT2A | |
| SCHEMBL790824 | 0.89 | ALPL (0.56) | ALPLSLC40A1PIK3CGPIK3CAPIK3CD | |
| SCHEMBL29556839 | 0.89 | ALPL (0.56) | ALPLSLC40A1PIK3CGPIK3CAPIK3CD | |
| SCHEMBL791429 | 0.86 | ALPL (0.47) | ALPLHSD17B10SLC40A1PIK3CGPIK3CA | |
| SCHEMBL15649596 | 0.84 | ALPL (0.40) | ALPLLMNAKDM4EHSD17B10KMT2A | |
| SCHEMBL9955288 | 0.83 | PIK3CG (0.52) | ALPLSLC40A1PIK3CGTSHRPIK3CA | |
| SCHEMBL3115744 | 0.82 | PIK3CD (0.57) | PIK3CGPIK3CAPIK3CDPIK3CBPIK3R1 | |
| SCHEMBL29555684 | 0.82 | PIK3CD (0.57) | PIK3CGPIK3CAPIK3CDPIK3CBPIK3R1 | |
| SCHEMBL798076 | 0.82 | ALPL (0.47) | ALPLKDM4EPIK3CGPIK3CAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |