Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980666 | 0.93 | RAB9A (0.74) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL7991544 | 0.90 | TP53 (0.61) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL7980693 | 0.87 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL8211088 | 0.84 | MAPK1 (0.57) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL7992673 | 0.84 | RAB9A (0.54) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL14451908 | 0.83 | HSD17B10 (0.71) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL7980980 | 0.83 | NPSR1 (0.59) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL10191988 | 0.82 | HPGD (0.71) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL10192012 | 0.82 | HPGD (0.56) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL7992789 | 0.82 | NPSR1 (0.76) | NPC1RAB9ASMN1; SMN2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294502-B1 | Thermally-responsive record material | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-25 | — | — | US | claimed |
| WO-1999061251-A1 | THERMALLY-RESPONSIVE RECORD MATERIAL CONTAINING A CARBAMATE COMPONENT | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-02 | — | — | WO | claimed |
| US-6294502-B1 | Thermally-responsive record material | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-25 | — | — | US | disclosed |
| WO-1999061251-A1 | THERMALLY-RESPONSIVE RECORD MATERIAL CONTAINING A CARBAMATE COMPONENT | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-02 | — | — | WO | disclosed |