Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980860 | 0.87 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL7991486 | 0.84 | KCNA5 (0.61) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL7994779 | 0.84 | NPC1 (0.80) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL7995865 | 0.82 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL7980666 | 0.81 | RAB9A (0.74) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL7992673 | 0.80 | RAB9A (0.54) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL7980732 | 0.79 | NPC1 (0.80) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL7994882 | 0.79 | NPC1 (0.80) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL7991544 | 0.78 | TP53 (0.61) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL5289703 | 0.78 | DRD2 (0.58) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294502-B1 | Thermally-responsive record material | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-25 | — | — | US | claimed |
| US-6294502-B1 | Thermally-responsive record material | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-25 | — | — | US | disclosed |
| WO-1999061251-A1 | THERMALLY-RESPONSIVE RECORD MATERIAL CONTAINING A CARBAMATE COMPONENT | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-02 | — | — | WO | disclosed |