Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5737927 | 0.81 | ESR2 (0.38) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL7981188 | 0.77 | ESR2 (0.30) | — | |
| SCHEMBL5735497 | 0.76 | — | — | |
| SCHEMBL5737256 | 0.75 | — | — | |
| SCHEMBL7578929 | 0.72 | — | — | |
| SCHEMBL6426280 | 0.71 | PTGS2 (0.41) | — | |
| SCHEMBL5736817 | 0.69 | HTR1D (0.39) | — | |
| SCHEMBL7578947 | 0.67 | — | — | |
| SCHEMBL5738571 | 0.66 | FFAR1 (0.43) | — | |
| SCHEMBL5735261 | 0.66 | RARA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303785-B1 | SUBSTITUTED N-CYCLOPROPYLTETRAHYDROISOQUINOLINES | ALLERGAN SALES, INC. | 2001-10-16 | — | — | US | disclosed |