Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7976797 | 0.98 | CA1 (0.39) | CA1CA2CA9ALDH1A1HSD17B10 | |
| SCHEMBL10351050 | 0.83 | CA1 (0.47) | CA1CA2CA9ALDH1A1HSD17B10 | |
| SCHEMBL7978251 | 0.77 | ALDH1A1 (0.52) | CA1CA2CA9ALDH1A1HSD17B10 | |
| SCHEMBL11715144 | 0.77 | CA1 (0.43) | CA1CA2CA9ALDH1A1HSD17B10 | |
| SCHEMBL21589350 | 0.77 | ALDH1A1 (0.55) | CA1CA2CA9ALDH1A1HSD17B10 | |
| SCHEMBL21589351 | 0.75 | ALDH1A1 (0.58) | CA1CA2CA9ALDH1A1HSD17B10 | |
| SCHEMBL17417188 | 0.75 | HTT (0.54) | CA1CA2ALDH1A1HSD17B10FABP3 | |
| SCHEMBL18523201 | 0.75 | ALDH1A1 (0.53) | CA1CA2CA9ALDH1A1HSD17B10 | |
| SCHEMBL13624547 | 0.75 | FABP3 (0.44) | CA1CA2ALDH1A1HSD17B10FABP3 | |
| SCHEMBL18746462 | 0.75 | MAPT (0.34) | ALDH1A1HSD17B10FABP3FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172239-B1 | PSYCHOLOGICAL, NERVOUS SYSTEM DISORDERS | SANOFI (FR) | 2001-01-09 | — | — | US | disclosed |
| US-5965579-A | ANTAGONISTS OF THE NEUROTENSIN RECEPTORS; INCREASING AFFINITY FOR HUMAN NEUROTENSIN RECEPTORS | SANOFI (FR) | 1999-10-12 | — | — | US | disclosed |
| US-5939449-A | NOVEL COMPOUNDS HAVING HIGH AFFINITY FOR THE NEUROTENSIN RECEPTORS | SANOFI (FR) | 1999-08-17 | — | — | US | disclosed |
| US-5936123-A | COMPOUNDS SUCH AS 3-ISOPROPYL-4-HYDRAZINOBENZOIC ACID AND ITS SALTS | SANOFI (FR) | 1999-08-10 | — | — | US | disclosed |
| US-5925661-A | NERVOUS SYSTEM DISORDERS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |
| CN-1184469-A | 1-phenyl-3-pyrazolecarboxamides active on neurotensin receptors | SANOFI SA (FR) | 1998-06-10 | — | — | CN | disclosed |
| US-5723483-A | NEUROTENSIN ANTAGONIST, HYPOTENSIVE AGENTS AND FOR NEUROPSYCHIATRIC DISORDERS | SANOFI (FR) | 1998-03-03 | — | — | US | disclosed |