Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.68 |
| ▸ | SRC | P12931 | 2/20 | 0.68 |
| ▸ | PRKACA | P17612 | 1/20 | 0.68 |
| ▸ | PRKACG | P22612 | 1/20 | 0.68 |
| ▸ | PRKACB | P22694 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981786 | 0.86 | SRC (0.56) | NOX4SRCPRKACAPRKACGPRKACB | |
| SCHEMBL6679443 | 0.83 | TP53 (0.51) | NOX4SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7970086 | 0.82 | SRC (0.63) | SRCPRKACAPRKACGPRKACBTP53 | |
| SCHEMBL7981707 | 0.81 | SRC (1.00) | NOX4SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7983884 | 0.80 | SRC (0.67) | SRCPRKACAPRKACGPRKACBKMT2A | |
| SCHEMBL7970466 | 0.79 | SRC (0.69) | NOX4SRCPRKACAPRKACGPRKACB | |
| SCHEMBL11445232 | 0.75 | KMT2A (0.53) | NOX4SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7980611 | 0.72 | SRC (0.60) | SRCKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29428154 | 0.71 | KDM4E (0.56) | TP53KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL28694312 | 0.71 | KDM4E (0.56) | TP53KMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277876-B1 | Matrix metalloproteinase inhibitors | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2001-08-21 | — | — | US | disclosed |
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0586608-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |