Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.67 |
| ▸ | PRKACA | P17612 | 1/20 | 0.67 |
| ▸ | PRKACG | P22612 | 1/20 | 0.67 |
| ▸ | PRKACB | P22694 | 1/20 | 0.67 |
| ▸ | CCR2 | P41597 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980495 | 0.85 | SRC (0.49) | SRCPRKACAPRKACGPRKACBCCR2 | |
| SCHEMBL7970086 | 0.84 | SRC (0.63) | SRCPRKACAPRKACGPRKACBKDM4E | |
| SCHEMBL7983999 | 0.80 | SRC (1.00) | SRCPRKACAPRKACGPRKACBCCR2 | |
| SCHEMBL7981572 | 0.80 | NOX4 (0.68) | SRCPRKACAPRKACGPRKACBKDM4E | |
| SCHEMBL7970466 | 0.78 | SRC (0.69) | SRCPRKACAPRKACGPRKACBKDM4E | |
| SCHEMBL7980611 | 0.74 | SRC (0.60) | SRCKDM4ETSHRMAPTMEN1 | |
| SCHEMBL9370571 | 0.71 | SRC (0.57) | SRCKDM4ETSHRMAPTKMT2A | |
| SCHEMBL2857645 | 0.71 | KDM4E (0.52) | KDM4ETSHRMAPTRXFP1MEN1 | |
| SCHEMBL2004745 | 0.70 | LMNA (0.60) | CCR2KDM4ETSHRMAPTABCB11 | |
| SCHEMBL13025171 | 0.70 | KDM4E (0.51) | KDM4ETSHRMAPTRXFP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |