Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 6/20 | 0.51 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | BRD1 | O95696 | 4/20 | 0.45 |
| ▸ | BRPF3 | Q9ULD4 | 3/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.45 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.45 |
| ▸ | PARG | Q86W56 | 4/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7984418 | 0.83 | F2 (0.59) | HDAC8HDAC6HDAC1TRIM24MAPK8 | |
| SCHEMBL7968319 | 0.82 | MEN1 (0.45) | BRD4F2 | |
| SCHEMBL7428683 | 0.78 | BRPF1 (0.52) | BRPF1SMARCA2IMPDH2HDAC8HDAC6 | |
| SCHEMBL7979565 | 0.78 | HDAC8 (0.46) | HDAC8HDAC6HDAC1PARG | |
| SCHEMBL8033052 | 0.76 | F2 (0.62) | BRPF1SMARCA2IMPDH2TRIM24BRD1 | |
| Hydrochloric Acid SCHEMBL7968287 | 0.75 | F2 (0.55) | F2 | |
| SCHEMBL7968478 | 0.74 | KMT2A (0.53) | HDAC8HDAC6HDAC1PARG | |
| SCHEMBL7479090 | 0.74 | BRPF1 (0.52) | BRPF1SMARCA2IMPDH2BRD1BRPF3 | |
| SCHEMBL8017541 | 0.74 | F2 (0.72) | BRPF1SMARCA2BRD1BRPF3BRD4 | |
| Hydrochloric Acid SCHEMBL7981610 | 0.72 | F2 (0.56) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |