Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | PARG | Q86W56 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968478 | 0.83 | KMT2A (0.53) | HDAC8HDAC6HDAC1MAPTPARG | |
| SCHEMBL7981601 | 0.78 | BRPF1 (0.51) | HDAC8HDAC6HDAC1PARG | |
| SCHEMBL25724069 | 0.75 | PARG (0.46) | HDAC8HDAC6HDAC1KDM4EALDH1A1 | |
| SCHEMBL7429478 | 0.73 | KDM4E (0.61) | HDAC8HDAC6HDAC1KDM4EALDH1A1 | |
| SCHEMBL7968319 | 0.72 | MEN1 (0.45) | ALDH1A1GAAMAPT | |
| SCHEMBL3240617 | 0.71 | ADORA2A (0.47) | ADORA2BADORA2AADORA3ADORA1 | |
| SCHEMBL14927365 | 0.69 | PGR (0.50) | ADORA2BADORA2APARG | |
| SCHEMBL7981152 | 0.68 | CYP11B1 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL9749159 | 0.67 | HPGD (0.68) | ALDH1A1GAAMAPTPARG | |
| SCHEMBL9748739 | 0.67 | CYP3A4 (0.68) | ALDH1A1GAAMAPTPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |