Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981944 | 0.83 | PTGIR (0.46) | PTGIROPRM1POLBHTTNPSR1 | |
| SCHEMBL9292204 | 0.82 | KMT2A (0.57) | OPRM1HPGDTRPM8POLBCYP2C19 | |
| SCHEMBL28682606 | 0.81 | PTGIR (0.44) | PTGIRSMN1; SMN2GAAPOLBHTT | |
| SCHEMBL7978941 | 0.81 | TP53 (0.51) | PTGIRSMN1; SMN2GAAPOLBHTT | |
| SCHEMBL18765715 | 0.80 | SMN1; SMN2 (0.56) | OPRM1SMN1; SMN2GAAKDM4EHPGD | |
| SCHEMBL7980229 | 0.80 | NPC1 (0.66) | PTGIRSMN1; SMN2KDM4ETRPM8POLB | |
| SCHEMBL7982394 | 0.80 | PTGIR (0.46) | PTGIRSMN1; SMN2GAAKDM4ETRPM8 | |
| SCHEMBL3948339 | 0.78 | HDAC1 (0.54) | — | |
| SCHEMBL7980404 | 0.78 | LTB4R2 (0.43) | PTGIRPOLBHTTNPSR1MEN1 | |
| SCHEMBL19512684 | 0.78 | NPSR1 (0.47) | PTGIRKDM4EHSD17B10POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |