Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.66 |
| ▸ | RAB9A | P51151 | 6/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MITF | O75030 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PTGIR | P43119 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981944 | 0.84 | PTGIR (0.46) | NPC1RAB9AALDH1A1KMT2ANPSR1 | |
| SCHEMBL7982394 | 0.84 | PTGIR (0.46) | NPC1RAB9AALDH1A1KMT2ANPSR1 | |
| SCHEMBL28682606 | 0.81 | PTGIR (0.44) | NPC1RAB9AALDH1A1KMT2ANPSR1 | |
| SCHEMBL7978941 | 0.81 | TP53 (0.51) | NPC1RAB9AALDH1A1KMT2ANPSR1 | |
| SCHEMBL10855054 | 0.81 | NPSR1 (0.50) | NPC1RAB9AALDH1A1KMT2ANPSR1 | |
| SCHEMBL2345303 | 0.80 | ALDH1A1 (1.00) | NPC1RAB9AALDH1A1KMT2ANPSR1 | |
| SCHEMBL7981765 | 0.80 | PTGIR (0.49) | KMT2ANPSR1HTTPOLBMEN1 | |
| SCHEMBL10668533 | 0.80 | NPSR1 (0.63) | NPC1RAB9AALDH1A1KMT2ANPSR1 | |
| SCHEMBL7980404 | 0.79 | LTB4R2 (0.43) | KMT2ANPSR1HTTPOLBMEN1 | |
| SCHEMBL3475461 | 0.78 | NPSR1 (0.47) | NPC1RAB9AALDH1A1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| CN-1252068-A | 3-piperidyl-4-oxoquinazoline derivatives and pharmaceutical compositions containing the same | JAPAN TOBACCO INC (JP) | 2000-05-03 | — | — | CN | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |