Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.43 |
| ▸ | PTGIR | P43119 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978941 | 0.91 | TP53 (0.51) | PTGIRHDAC6TP53POLBHTT | |
| SCHEMBL7981944 | 0.85 | PTGIR (0.46) | PTGIRPOLBHTTNPSR1MEN1 | |
| SCHEMBL7978813 | 0.83 | ALDH1A1 (0.55) | LTB4R2TP53POLBHTTNPSR1 | |
| SCHEMBL2205203 | 0.81 | LTB4R2 (0.52) | LTB4R2TP53POLBHTTNPSR1 | |
| SCHEMBL28682606 | 0.79 | PTGIR (0.44) | PTGIRHDAC6TP53POLBHTT | |
| SCHEMBL27471455 | 0.79 | POLB (0.43) | LTB4R2HDAC6POLBHTTMEN1 | |
| SCHEMBL7980229 | 0.79 | NPC1 (0.66) | PTGIRTP53POLBHTTNPSR1 | |
| SCHEMBL7982394 | 0.79 | PTGIR (0.46) | PTGIRTP53POLBHTTNPSR1 | |
| SCHEMBL7104669 | 0.79 | FFAR1 (0.42) | PTGIRHDAC6TP53POLBHTT | |
| SCHEMBL7981765 | 0.78 | PTGIR (0.49) | PTGIRTP53POLBHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |