Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11464553 | 0.89 | MEN1 (0.50) | OPRM1POLBHTTNPSR1KMT2A | |
| SCHEMBL7978941 | 0.88 | TP53 (0.51) | PTGIRPOLBHTTNPSR1KMT2A | |
| SCHEMBL7980404 | 0.85 | LTB4R2 (0.43) | PTGIRPOLBHTTNPSR1KMT2A | |
| SCHEMBL28682606 | 0.84 | PTGIR (0.44) | PTGIRPOLBHTTNPSR1KMT2A | |
| SCHEMBL7980229 | 0.84 | NPC1 (0.66) | PTGIRPOLBHTTNPSR1KMT2A | |
| SCHEMBL7982394 | 0.84 | PTGIR (0.46) | PTGIRPOLBHTTNPSR1KMT2A | |
| SCHEMBL7981765 | 0.83 | PTGIR (0.49) | PTGIROPRM1POLBHTTNPSR1 | |
| SCHEMBL11464552 | 0.82 | OPRM1 (0.47) | OPRM1POLBHTTNPSR1KMT2A | |
| SCHEMBL2170751 | 0.82 | OPRM1 (0.38) | PTGIROPRM1POLBHTTNPSR1 | |
| SCHEMBL19512684 | 0.81 | NPSR1 (0.47) | PTGIRPOLBHTTNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| CN-1252068-A | 3-piperidyl-4-oxoquinazoline derivatives and pharmaceutical compositions containing the same | JAPAN TOBACCO INC (JP) | 2000-05-03 | — | — | CN | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |