Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981836 | 0.78 | TDP1 (0.38) | CYP3A4MAPTL3MBTL1 | |
| SCHEMBL3162729 | 0.75 | RAB9A (0.35) | POLBCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL11456937 | 0.73 | SIGMAR1 (0.48) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL11446418 | 0.70 | SIGMAR1 (0.46) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| SCHEMBL7981785 | 0.69 | ATM (0.43) | MAPTMEN1KMT2ABCHESMN1; SMN2 | |
| SCHEMBL7969037 | 0.69 | TSHR (0.36) | SIGMAR1KDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL27006694 | 0.68 | MME (0.47) | SIGMAR1POLBMAPTSMN1; SMN2RIPK1 | |
| SCHEMBL18775067 | 0.68 | SIGMAR1 (0.43) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| SCHEMBL18775068 | 0.68 | MME (0.47) | SIGMAR1POLBMAPTSMN1; SMN2RIPK1 | |
| SCHEMBL24326403 | 0.68 | ATM (0.52) | POLBMAPTMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |