Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3475493 | 0.82 | MEN1 (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9185293 | 0.78 | TRPA1 (0.40) | CYP2D6MAOA | |
| SCHEMBL7969044 | 0.72 | POLB (0.37) | BCHEALDH1A1OPRK1 | |
| SCHEMBL13308364 | 0.71 | ANPEP (0.51) | ATMMEN1KMT2ATDP1BCHE | |
| SCHEMBL31675971 | 0.71 | ALDH1A1 (0.51) | ATMMEN1KMT2ATDP1BCHE | |
| SCHEMBL8635730 | 0.71 | KMT2A (0.52) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL28998160 | 0.70 | MEN1 (0.41) | ATMMEN1KMT2ATDP1BCHE | |
| SCHEMBL7981778 | 0.69 | SIGMAR1 (0.45) | MEN1KMT2ABCHESMN1; SMN2MAPT | |
| SCHEMBL13995600 | 0.69 | MEN1 (0.52) | MEN1KMT2ATDP1BCHEANPEP | |
| SCHEMBL13995906 | 0.69 | MEN1 (0.52) | MEN1KMT2ATDP1BCHEANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |