Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | BACE1 | P56817 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 4/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3926872 | 0.91 | BACE1 (0.71) | TDP1BACE1KMT2AL3MBTL1MEN1 | |
| SCHEMBL10914560 | 0.91 | BACE1 (0.71) | TDP1BACE1KMT2AL3MBTL1MEN1 | |
| SCHEMBL1504320 | 0.89 | TDP1 (0.59) | TDP1BACE1KMT2AL3MBTL1CTSL | |
| SCHEMBL14534184 | 0.88 | CTSL (0.67) | TDP1KMT2AL3MBTL1MEN1CTSL | |
| SCHEMBL20335144 | 0.88 | CTSL (0.67) | TDP1KMT2AL3MBTL1MEN1CTSL | |
| SCHEMBL7984123 | 0.88 | POLB (0.60) | BACE1KMT2AL3MBTL1MEN1CTSL | |
| SCHEMBL8057955 | 0.88 | TDP1 (0.62) | TDP1BACE1KMT2AL3MBTL1MEN1 | |
| SCHEMBL20335146 | 0.88 | CTSL (0.67) | TDP1KMT2AL3MBTL1MEN1CTSL | |
| SCHEMBL30689128 | 0.87 | CTSL (0.63) | TDP1BACE1KMT2AL3MBTL1MEN1 | |
| SCHEMBL4522161 | 0.87 | TDP1 (0.79) | TDP1KMT2AL3MBTL1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284912-B1 | Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives | LG CHEMICAL, LTD. (KR) | 2001-09-04 | — | — | US | disclosed |
| EP-1043309-A1 | Process for synthesizing para-and/or meta-substituted cyanophenylalanine derivatives | LG Chemical Ltd. (KR) | 2000-10-11 | — | — | EP | disclosed |