Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | BACE1 | P56817 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MDM4 | O15151 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 7/20 | 0.54 |
| ▸ | MMP9 | P14780 | 6/20 | 0.54 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27568136 | 0.92 | POLB (0.70) | POLBMEN1KMT2ACA12CA7 | |
| SCHEMBL13226933 | 0.90 | POLB (0.60) | POLBBACE1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8057955 | 0.90 | TDP1 (0.62) | POLBBACE1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7981960 | 0.88 | TDP1 (0.60) | POLBBACE1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8912956 | 0.86 | L3MBTL1 (0.78) | POLBMEN1KMT2AL3MBTL1MMP2 | |
| SCHEMBL13208269 | 0.86 | ALDH1A1 (0.72) | POLBMEN1KMT2AL3MBTL1CA12 | |
| SCHEMBL7189021 | 0.86 | POLB (0.57) | POLBBACE1MEN1KMT2ACA12 | |
| SCHEMBL7984105 | 0.86 | BACE1 (0.62) | POLBBACE1MEN1KMT2AL3MBTL1 | |
| SCHEMBL15943338 | 0.85 | MMP2 (0.75) | POLBMEN1KMT2ACA12CA7 | |
| SCHEMBL7981740 | 0.85 | MMP2 (0.56) | POLBMEN1KMT2ACA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284912-B1 | Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives | LG CHEMICAL, LTD. (KR) | 2001-09-04 | — | — | US | disclosed |
| EP-1043309-A1 | Process for synthesizing para-and/or meta-substituted cyanophenylalanine derivatives | LG Chemical Ltd. (KR) | 2000-10-11 | — | — | EP | disclosed |