Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 1/20 | 1.00 |
| ▸ | CASP1 | P29466 | 1/20 | 1.00 |
| ▸ | MPI | P34949 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | CASP7 | P55210 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19962697 | 0.77 | KMT2A (0.61) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL68581 | 0.76 | MEN1 (0.61) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL1756450 | 0.75 | CASP1 (0.59) | MEN1KMT2AALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL29473284 | 0.75 | MEN1 (0.59) | MEN1KMT2AALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL7142299 | 0.75 | MEN1 (0.59) | MEN1KMT2AALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL5512697 | 0.75 | MEN1 (0.59) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL6294041 | 0.74 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL9803751 | 0.73 | MEN1 (0.58) | MEN1KMT2AALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL30205268 | 0.73 | MEN1 (0.58) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL9538393 | 0.73 | MEN1 (0.58) | MEN1KMT2AALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274596-B1 | MICROBIOCIDES FOR DRUG RESISTANCE INFECTIONS | ANADYS PHARMACEUTICALS, INC. | 2001-08-14 | — | — | US | disclosed |
| WO-2000024389-A2 | BENZOQUINOLINE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | ANADYS PHARMACEUTICALS, INC. (US) | 2000-05-04 | — | — | WO | disclosed |