Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 3/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.32 |
| ▸ | ATF1 | P18846 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 7/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794556 | 0.93 | PDE5A (0.33) | CCR4TRPV1PDE5APTGES | |
| SCHEMBL17857812 | 0.92 | NR1H2 (0.35) | PTPN11CCR4ATF1NFKB1PDE5A | |
| SCHEMBL17857814 | 0.90 | PTGES (0.35) | TRPV1PTGES | |
| SCHEMBL797864 | 0.89 | CCR4 (0.36) | CCR4METAP2 | |
| SCHEMBL15467152 | 0.88 | ATF1 (0.40) | PTPN11CCR4TRPV1ATF1NFKB1 | |
| SCHEMBL15466275 | 0.85 | CCR4 (0.33) | CCR4TRPV1PDE5A | |
| SCHEMBL15466511 | 0.84 | PDE5A (0.34) | CCR4PDE5A | |
| SCHEMBL796012 | 0.82 | CCR4 (0.35) | CCR4TRPV1PTGES | |
| SCHEMBL796070 | 0.82 | NR1H2 (0.35) | PTGES | |
| SCHEMBL3030705 | 0.81 | NR1H2 (0.35) | CCR4TRPV1ATF1NFKB1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375000-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
| EP-2616437-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035011-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | DDT, ACHE, CAT | PTPN11 654/4885CCR4 215/4885TRPV1 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.