Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF1 | P18846 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.33 |
| ▸ | PDE5A | O76074 | 5/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030705 | 0.92 | NR1H2 (0.35) | ATF1NFKB1NR1H2NR1H3TRPV1 | |
| SCHEMBL15466715 | 0.91 | NR1H2 (0.44) | ATF1NFKB1NR1H2NR1H3PTPN11 | |
| SCHEMBL15466559 | 0.91 | NR1H2 (0.36) | ATF1NFKB1NR1H2NR1H3CYP1A2 | |
| SCHEMBL798260 | 0.89 | ATF1 (0.40) | ATF1NFKB1NR1H2NR1H3CYP2C9 | |
| SCHEMBL798197 | 0.88 | PTPN11 (0.33) | ATF1NFKB1PTPN11TRPV1PDE5A | |
| SCHEMBL15465826 | 0.85 | TRPV1 (0.37) | TRPV1CYP1A2CYP2C9GRIA2EPHX2 | |
| SCHEMBL793715 | 0.85 | NR1H2 (0.35) | ATF1NFKB1NR1H2NR1H3TRPV1 | |
| SCHEMBL2308717 | 0.84 | NR1H2 (0.42) | ATF1NFKB1NR1H2NR1H3PDE5A | |
| SCHEMBL15466757 | 0.84 | P2RX7 (0.34) | TRPV1EPHX2NR1H4 | |
| SCHEMBL794978 | 0.82 | NR1H2 (0.43) | ATF1NFKB1NR1H2NR1H3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375000-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | DDT, ACHE, CAT | ATF1 937/4885NFKB1 3428/4885NR1H2 2771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.