Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16881232 | 0.84 | CASP3 (0.37) | GAAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL7395719 | 0.82 | GAA (0.34) | GAAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL4298018 | 0.75 | APOBEC3G (0.32) | — | |
| SCHEMBL3825675 | 0.73 | HSD17B10 (0.44) | GAATSHRKDM4ERECQLCASP3 | |
| SCHEMBL7398237 | 0.71 | KDM4E (0.32) | GAAMEN1KMT2AKDM4ERECQL | |
| SCHEMBL6702689 | 0.70 | AR (0.31) | ALDH1A1 | |
| SCHEMBL6296564 | 0.70 | NPSR1 (0.33) | CYP1A2ALDH1A1 | |
| SCHEMBL8338137 | 0.69 | CASP3 (0.46) | GAAMEN1KMT2ACYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL8341619 | 0.68 | CASP3 (0.45) | GAAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL23748314 | 0.67 | CASP3 (0.47) | GAAMEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |