Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988358 | 0.91 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL7984967 | 0.87 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL5671154 | 0.81 | HSD17B10 (0.61) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL3250724 | 0.72 | HSD17B10 (0.58) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL7985003 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL5671626 | 0.70 | HSD17B10 (0.65) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL10738044 | 0.69 | IDO1 (0.48) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL8853387 | 0.68 | BRD4 (0.61) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL9628743 | 0.66 | BRD4 (0.51) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL10730206 | 0.66 | HSD17B10 (0.63) | ALDH1A1MEN1KMT2AMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191127-B1 | ANTIINFLAMMATORY AGENTS, AUTOIMMUNE DISEASES, CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |