Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969852 | 0.79 | MAPT (0.51) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL7984967 | 0.74 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL10932712 | 0.73 | MEN1 (0.65) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL7982017 | 0.71 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL7988358 | 0.69 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL12571712 | 0.68 | IDO1 (0.52) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL10358553 | 0.67 | KDM4E (0.51) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL8853841 | 0.67 | MEN1 (1.00) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL9802392 | 0.66 | MAPT (0.45) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL7982133 | 0.63 | PARP1 (0.45) | ALDH1A1MAPTBRD4CREBBPTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191127-B1 | ANTIINFLAMMATORY AGENTS, AUTOIMMUNE DISEASES, CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |