Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982025 | 1.00 | GRIN2B (0.39) | GRIN2BHRH3SIGMAR1CCR3DRD2 | |
| Hydrochloric Acid SCHEMBL7973069 | 0.99 | GRIN2B (0.39) | GRIN2BHRH3SIGMAR1CCR3DRD2 | |
| Hydrochloric Acid SCHEMBL7973066 | 0.99 | GRIN2B (0.39) | GRIN2BHRH3SIGMAR1CCR3DRD2 | |
| SCHEMBL7985592 | 0.84 | HTR2A (0.39) | GRIN2BHRH3SIGMAR1CCR3DRD2 | |
| SCHEMBL7985591 | 0.84 | HTR2A (0.39) | GRIN2BHRH3SIGMAR1CCR3DRD2 | |
| Hydrochloric Acid SCHEMBL7985606 | 0.83 | HTR2A (0.38) | GRIN2BHRH3SIGMAR1CCR3DRD2 | |
| Hydrochloric Acid SCHEMBL7985599 | 0.83 | HTR2A (0.38) | GRIN2BHRH3SIGMAR1CCR3DRD2 | |
| SCHEMBL7985968 | 0.82 | HRH3 (0.38) | GRIN2BHRH3SIGMAR1CCR3DRD2 | |
| SCHEMBL7985972 | 0.82 | HRH3 (0.38) | GRIN2BHRH3SIGMAR1CCR3DRD2 | |
| SCHEMBL7986511 | 0.82 | ALDH1A1 (0.43) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |