Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985972 | 1.00 | HRH3 (0.38) | HRH3CHRM4SIGMAR1CCR3CHRNB2 | |
| Hydrochloric Acid SCHEMBL7985894 | 0.99 | HRH3 (0.38) | HRH3CHRM4SIGMAR1CCR3CHRNB2 | |
| Hydrochloric Acid SCHEMBL7985896 | 0.99 | HRH3 (0.38) | HRH3CHRM4SIGMAR1CCR3CHRNB2 | |
| SCHEMBL7986505 | 0.87 | ALDH1A1 (0.43) | ALDH1A1BLMKDM4ELMNAGAA | |
| SCHEMBL7986511 | 0.87 | ALDH1A1 (0.43) | ALDH1A1BLMKDM4ELMNAGAA | |
| SCHEMBL7986125 | 0.87 | LTA4H (0.44) | CHRM4CCR3CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7971710 | 0.87 | LTA4H (0.44) | CHRM4CCR3CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL7989634 | 0.86 | ALDH1A1 (0.42) | ALDH1A1BLMKDM4ELMNAGAA | |
| Hydrochloric Acid SCHEMBL7989632 | 0.86 | ALDH1A1 (0.42) | ALDH1A1BLMKDM4ELMNAGAA | |
| Hydrochloric Acid SCHEMBL7984719 | 0.86 | LTA4H (0.43) | CHRM4CCR3CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |