Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986505 | 1.00 | ALDH1A1 (0.43) | ALDH1A1BLMKCNH2KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL7989634 | 0.99 | ALDH1A1 (0.42) | ALDH1A1BLMKCNH2KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL7989632 | 0.99 | ALDH1A1 (0.42) | ALDH1A1BLMKCNH2KDM4ELMNA | |
| SCHEMBL7989409 | 0.88 | DRD4 (0.44) | ALDH1A1BLMHTR2A | |
| SCHEMBL7989406 | 0.88 | DRD4 (0.44) | ALDH1A1BLMHTR2A | |
| Hydrochloric Acid SCHEMBL7986140 | 0.87 | DRD4 (0.43) | ALDH1A1BLMHTR2A | |
| Hydrochloric Acid SCHEMBL7986142 | 0.87 | DRD4 (0.43) | ALDH1A1BLMHTR2A | |
| SCHEMBL7985972 | 0.87 | HRH3 (0.38) | ALDH1A1BLMKDM4ELMNAGAA | |
| SCHEMBL7985968 | 0.87 | HRH3 (0.38) | ALDH1A1BLMKDM4ELMNAGAA | |
| Hydrochloric Acid SCHEMBL7985894 | 0.86 | HRH3 (0.38) | ALDH1A1BLMKDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |