Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670512 | 0.76 | KDM4E (0.38) | NOS3NOS1NOS2KDM4EALDH1A1 | |
| SCHEMBL5670575 | 0.71 | ESR1 (0.35) | — | |
| SCHEMBL7982290 | 0.71 | AHR (0.33) | NOS1NOS2 | |
| SCHEMBL5670724 | 0.69 | ESR1 (0.46) | NOS3NOS1NOS2KDM4EALDH1A1 | |
| SCHEMBL7710726 | 0.64 | ALDH1A1 (0.45) | NOS3NOS1NOS2ALDH1A1LMNA | |
| SCHEMBL5670594 | 0.62 | CYP1A2 (0.43) | NOS3NOS1NOS2KDM4EALDH1A1 | |
| SCHEMBL68914 | 0.62 | SIRT2 (0.44) | — | |
| SCHEMBL30576350 | 0.62 | SIRT2 (0.44) | — | |
| SCHEMBL7985549 | 0.61 | MAPT (0.43) | NOS3NOS1NOS2KDM4EALDH1A1 | |
| SCHEMBL7984721 | 0.61 | MAPT (0.43) | NOS3NOS1NOS2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191127-B1 | ANTIINFLAMMATORY AGENTS, AUTOIMMUNE DISEASES, CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |