Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985549 | 0.73 | MAPT (0.43) | AHRNOS1NOS2 | |
| SCHEMBL7985616 | 0.68 | MAPT (0.47) | NOS1NOS2 | |
| SCHEMBL5670575 | 0.63 | ESR1 (0.35) | — | |
| SCHEMBL8188553 | 0.62 | NOS3 (0.34) | NOS1NOS2 | |
| SCHEMBL6993506 | 0.59 | KDM4E (0.34) | NOS1NOS2 | |
| SCHEMBL7708028 | 0.57 | NOS3 (0.43) | NOS1NOS2 | |
| SCHEMBL8952151 | 0.56 | AHR (0.82) | AHR | |
| SCHEMBL31405545 | 0.55 | ALDH1A1 (0.41) | AHR | |
| SCHEMBL657760 | 0.54 | ALDH1A1 (0.65) | AHR | |
| SCHEMBL8952199 | 0.52 | AHR (0.64) | AHREZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191127-B1 | ANTIINFLAMMATORY AGENTS, AUTOIMMUNE DISEASES, CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |