SCHEMBL7982275

SCHEMBL7982275

Cc1ccc(C(=O)NC(C)CCOc2c(Cl)cc(O)cc2Cl)s1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 2/20 0.46
TAS1R1 Q7RTX1 2/20 0.46
KMT2A Q03164 5/20 0.38
POLB P06746 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NPC1 O15118 6/20 0.37
MEN1 O00255 4/20 0.37
RAB9A P51151 5/20 0.36
CASP3 P42574 2/20 0.36
SENP7 Q9BQF6 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
MAPT P10636 3/20 0.36
LMNA P02545 3/20 0.36
PLAU P00749 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
AKT3 Q9Y243 1/20 0.36
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27559616 0.83 TAS1R3 (0.44) TAS1R3TAS1R1KMT2APOLBTDP1
SCHEMBL8063185 0.81 NPC1 (0.51) KMT2APOLBTDP1NPC1RAB9A
SCHEMBL7979212 0.80 NPC1 (0.50) KMT2APOLBTDP1NPC1MEN1
SCHEMBL7965729 0.76 KMT2A (0.55) KMT2AMEN1RAB9ANPSR1MAPT
SCHEMBL12124251 0.70 TAS1R3 (0.63) TAS1R3TAS1R1KMT2APOLBTDP1
SCHEMBL8067389 0.65 NPC1 (0.44) KMT2APOLBTDP1NPC1RAB9A
SCHEMBL13753495 0.65 TAS1R3 (0.59) TAS1R3TAS1R1KMT2APOLBTDP1
SCHEMBL14846340 0.65 LIPG (0.61)
SCHEMBL15901974 0.65 LIPG (0.61)
SCHEMBL4206056 0.64 TAS1R3 (1.00) TAS1R3TAS1R1KMT2APOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed
EP-0824514-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-09-06 EP disclosed
US-6028100-A Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-22 US disclosed
US-5952386-A EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-14 US disclosed
WO-1996033160-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-10-24 WO disclosed