Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670842 | 0.83 | ALDH1A1 (0.65) | ALDH1A1HPGDMAPK1HSD17B10GAA | |
| SCHEMBL5672408 | 0.78 | ALDH1A1 (0.40) | EGFRALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL7985016 | 0.78 | PGR (0.45) | EGFRALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL5670843 | 0.78 | PARP1 (0.45) | ALDH1A1HPGDMAPK1HSD17B10GAA | |
| SCHEMBL5672871 | 0.77 | ALDH1A1 (0.41) | EGFRALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL7988315 | 0.75 | PARP1 (0.42) | ALDH1A1HPGDMAPK1HSD17B10GAA | |
| SCHEMBL7988038 | 0.73 | PGR (0.48) | ALDH1A1HPGDMAPK1HSD17B10USP2 | |
| SCHEMBL7980818 | 0.72 | PARP1 (0.46) | EGFRALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL5672792 | 0.72 | BRD4 (0.41) | ALDH1A1HPGDMAPK1HSD17B10GAA | |
| SCHEMBL7985006 | 0.71 | PGR (0.50) | ALDH1A1MAPK1HSD17B10USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191127-B1 | ANTIINFLAMMATORY AGENTS, AUTOIMMUNE DISEASES, CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |