Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672871 | 0.86 | ALDH1A1 (0.41) | PGRALDH1A1MAPK1HSD17B10BRD4 | |
| SCHEMBL5670687 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPK1HSD17B10BRD4PARP1 | |
| SCHEMBL5670843 | 0.80 | PARP1 (0.45) | ALDH1A1MAPK1HSD17B10BRD4NR3C1 | |
| SCHEMBL7982283 | 0.78 | EGFR (0.54) | ALDH1A1MAPK1HSD17B10HPGDUSP2 | |
| SCHEMBL7988315 | 0.77 | PARP1 (0.42) | PGRALDH1A1MAPK1HSD17B10BRD4 | |
| SCHEMBL5672408 | 0.77 | ALDH1A1 (0.40) | ALDH1A1MAPK1HSD17B10BRD4NR3C1 | |
| Hydrochloric Acid SCHEMBL9427252 | 0.75 | SLC6A2 (0.49) | — | |
| SCHEMBL7988038 | 0.75 | PGR (0.48) | PGRALDH1A1MAPK1HSD17B10BRD4 | |
| SCHEMBL5672792 | 0.74 | BRD4 (0.41) | PGRALDH1A1MAPK1HSD17B10BRD4 | |
| SCHEMBL7985006 | 0.73 | PGR (0.50) | PGRALDH1A1MAPK1HSD17B10BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191127-B1 | ANTIINFLAMMATORY AGENTS, AUTOIMMUNE DISEASES, CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |