Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 1/20 | 0.57 |
| ▸ | HPRT1 | P00492 | 10/20 | 0.56 |
| ▸ | PNP | P00491 | 5/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EDNRA | P25101 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HBB | P68871 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570078 | 0.89 | TK1 (0.65) | TK1HPRT1PNPUSP2TSHR | |
| SCHEMBL7575116 | 0.89 | TK1 (0.59) | TK1HPRT1PNPUSP2TSHR | |
| SCHEMBL7567095 | 0.88 | TK1 (0.60) | TK1HPRT1PNPUSP2TSHR | |
| SCHEMBL7572289 | 0.87 | TK1 (0.60) | TK1HPRT1PNPUSP2TSHR | |
| SCHEMBL7576803 | 0.87 | TK1 (0.60) | TK1HPRT1PNP | |
| SCHEMBL7567140 | 0.84 | PNP (0.64) | TK1HPRT1PNPUSP2TSHR | |
| SCHEMBL7570457 | 0.84 | TK1 (0.56) | TK1HPRT1PNPBLM | |
| SCHEMBL7392166 | 0.83 | HPRT1 (0.54) | HPRT1PNP | |
| SCHEMBL7980835 | 0.83 | HPRT1 (0.50) | TK1HPRT1PNPUSP2TSHR | |
| SCHEMBL7567195 | 0.82 | HPRT1 (0.51) | TK1HPRT1PNPUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297226-B1 | TREATING A DISEASE OR A CONDITION IN A MAMMAL TREATABLE BY INHIBITING THE ACTIVITY OF A MONOAMINE OXIDASE | NEOTHERAPEUTICS, INC. | 2001-10-02 | — | — | US | claimed |
| US-6297226-B1 | TREATING A DISEASE OR A CONDITION IN A MAMMAL TREATABLE BY INHIBITING THE ACTIVITY OF A MONOAMINE OXIDASE | NEOTHERAPEUTICS, INC. | 2001-10-02 | — | — | US | disclosed |