Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853160 | 0.85 | APP (0.49) | APPHTR1ADRD2MAPTMAPK1 | |
| SCHEMBL11647126 | 0.82 | APP (0.56) | APPHTR1ADRD2MAPTMAPK1 | |
| SCHEMBL31375355 | 0.82 | APP (0.56) | APPHTR1ADRD2MAPTMAPK1 | |
| SCHEMBL11846878 | 0.80 | PTGER1 (0.53) | HPGD | |
| SCHEMBL11840264 | 0.80 | L3MBTL1 (0.49) | HTR1ADRD2MAPTMAPK1TDP1 | |
| SCHEMBL11839270 | 0.80 | CCR5 (0.56) | SMN1; SMN2MAOB | |
| SCHEMBL11611970 | 0.80 | MAPT (0.51) | HTR1ADRD2MAPTMAPK1TDP1 | |
| SCHEMBL6819629 | 0.79 | ELANE (0.47) | HTR1ADRD2MAPTALOX5HPGD | |
| SCHEMBL11844159 | 0.79 | MAPK1 (0.46) | HTR1ADRD2MAPTMAPK1TDP1 | |
| SCHEMBL10601013 | 0.78 | DRD2 (0.69) | HTR1ADRD2MAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3987108-A | INSECTICIDES, ACARICIDES | CIBA-GEIGY CORPORATION (US) | 1976-10-19 | — | — | US | claimed |