Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.34 |
| ▸ | TUBB | P07437 | 3/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7250879 | 0.93 | NPSR1 (0.42) | MGAMGAASIMGAM2NPSR1 | |
| SCHEMBL7249419 | 0.86 | ALDH1A1 (0.41) | L3MBTL1TDP1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL7982354 | 0.81 | ALDH1A1 (0.40) | NPSR1TDP1ALDH1A1TUBB4ATUBB | |
| SCHEMBL2947942 | 0.75 | TDP1 (0.59) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL29337154 | 0.73 | ALDH1A1 (0.57) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL5367353 | 0.68 | ALDH1A1 (0.38) | NPSR1L3MBTL1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2949659 | 0.68 | TDP1 (0.54) | NPSR1L3MBTL1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8960775 | 0.68 | TDP1 (0.53) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL419987 | 0.67 | NPSR1 (0.59) | NPSR1L3MBTL1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30486812 | 0.67 | NPSR1 (0.59) | NPSR1L3MBTL1TDP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001077116-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-10-18 | — | — | WO | disclosed |